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Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it should be ensured that if antibiotics are required, that they are given in effective doses. Deltasone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisone typically does not produce immediate effects and must be used for several days before the needed effect is achieved. Deltasone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases. Steroid medication needs may change if you have a fungal infection anywhere in your body. Steroid medication can weaken your immune system, making it easier for you to get an infection.