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Metformin belongs to the class of drugs known as biguanides. Metformin comes as a tablet and an extended-release tablet to take by mouth. You naturally produce, and by decreasing the amount of sugar in your blood by decreasing sugar production and absorption and helping your body respond better to its own insulin, which promotes the burning of sugar. Metformin also increases your body's proper response to the insulin you naturally produce, and by decreasing the amount of glucose made by your liver. Glucophage should be taken with meals. By decreasing the amount of glucose you absorb from your food and the amount of sugar produced by cells in the liver. Metformin also increases your body's proper response to the insulin you naturally produce, and by decreasing the amount of glucose in the blood. Metformin is used as a first line treatment of type 2 diabetes.