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Glucophage should be taken with meals. Glucophage lowers the amount of sugar produced by cells in the liver. Metformin increases the sensitivity of muscle cells to insulin. Metformin delays absorption of sugar from the blood hence in type 2 diabetes in people who are at high risk for becoming diabetic. Metformin decreases the amount of sugar produced by cells in the liver. Glucophage should be taken with meals. By the pancreas called insulin.
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