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Prednisone, are commonly used to suppress the immune system to attack by micro-organisms, it should be noted that it is very different from another group of steroids, called anabolic steroids, which have gained notoriety because of their abuse by some athletes and body builders. Prednisone is used in so many conditions, only the most common or established uses are mentioned here. Prednisolone works by acting within cells to prevent the release of substances in the body. Prednisolone is a corticosteroid medicine.