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As a result, people with panic disorder develop an intense fear of having another attack. You start feeling better and unpleasant side effects may be experienced if you stop taking Paxil suddenly. Your doctor if you experience headache nervousness, or anxiety nausea, diarrhea, or changes in appetite or weight. You, you are now taking an FDA-approved medication proven safe and effective for long-term use and is well tolerated. With depression, the most severe cognitive and behavioral malfunctions are expressed in what is called a major depressive disorder, which is also called clinical depression.